Annabelle is a murderous fictional doll from a series of horror films bearing her name. She is based on an actual doll that is believed to be haunted.[1]
As Stewie sorts photos in the attic to make a collage for Rupert in "The Talented Mr. Stewie", he has to reassure her that he doesn't need anyone killed. When Brian enters and says that he thinks the project is stupid, Stewie seeks assurance from Annabelle, but finds she's already left, as Peter can be heard reacting to her downstairs