Ariel Fernandez
Ariel Fernandez | |
|---|---|
 | |
| Born | April 8, 1957 |
| Citizenship | Argentina, USA |
| Alma mater | Yale University |
| Scientific career | |
| Fields | Biophysics |
| Institutions | Instituto Argentino de Matematica |
| Doctoral advisor | Oktay Sinanoglu |
Ariel Fernandez (born April 8, 1957) is an Argentinian–American physical chemist.
Biography
He was born Ariel Fernandez Stigliano in Bahía Blanca, Argentina, and received a Licenciado in Matematica in 1980 from the Universidad Nacional del Sur, Bahia Blanca, Argentina. He then earned a Ph. D. in chemical physics from Yale University in 1984 and was post-doctoral fellow under Manfred Eigen in Goettingen. He held the Karl F. Hasselmann Chaired Professorship in Engineering at Rice University during the period 2005-2010. He is a member of the National Scientific and Technical Research Council (CONICET) in Argentina and conducts research at Instituto Argentino de Matematica in Buenos Aires.[1]
He is president of AF Innovation, an Argentine consultancy firm in molecular engineering.
Research
His research spans representation theory in algebra, physical chemistry, molecular biophysics, and more recently, molecular evolution and drug discovery.
He pioneered wrapping technology and outlined its therapeutic possibilities in his book Transformative Concepts for Drug Design: Target Wrapping.[2] He developed the concept of the dehydron, a structural feature in a protein, consisting of an intramolecular hydrogen bond incompletely shielded from water attack, thereby endowed with a propensity to promote its own dehydration.
Awards
Camille and Henry Dreyfus Distinguished New Faculty, 1989; Camille and Henry Dreyfus Teacher-Scholar, 1991; Humboldt Award; John Simon Guggenheim Memorial Foundation Fellow, 1995;[3] Feinberg Fellow; State of Buenos Aires Medal; Eli Lilly Awardee; Honorary Member of Collegium Basilea (Switzerland); Elected Fellow, American Institute for Medical and Biological Engineering (2006).[4]
Concerns about results
In April 2013, the journal BMC Genomics issued an expression of concern about a 2011 research article by Fernández and others[5] [6]. It states that the data generated by Fernández "seemed anomalous", and reports that there were investigations by two of his institutions. One institution determined that the results were not reproducible by the methods described in the article, while the other found nothing suspicious. Given the conflicting conclusions of these investigations, the BMC Genomics editors advise readers to interpret the data with due caution and apologize to all affected parties.[7]
References
- ^ "Ariel Fernández". Instituto Argentino de Matematica. Retrieved 27 September 2012.
- ^ Fernandez, Ariel. Transformative Concepts for Drug Design: Target Wrapping. (ISBN 978-3642117916), Springer-Verlag, Berlin, Heidelberg, 2010.
- ^ "Ariel Fernández". Fellows. John Simon Guggenheim Memorial Foundation. Retrieved 27 September 2012.
- ^ "College of Fellows". Members. American Institute for Medical and Biological Engineering. Retrieved 27 September 2012.
- ^ "Expression of concern in BMC Genomics"
- ^ "Discussion of expression of concern at Retraction Watch"
- ^ "Expression of concern in BMC Genomics"
External links
- Ariel Fernandez Mathematics Research at IAM (Buenos Aires, Argentina)
- Ariel Fernandez Innovation Consultancy
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