NEU2

NEU2
Strwythurau PDB Human UniProt search: PDBe RCSB Rhestr o ddynodwyr PDB 1SNT, 1SO7, 1VCU, 2F0Z, 2F10, 2F11, 2F12, 2F13, 2F24, 2F25, 2F26, 2F27, 2F28, 2F29, 4NC5, 4NCS
Dynodwyr
Cyfenwau	NEU2, SIAL2, neuraminidase 2 (cytosolic sialidase), neuraminidase 2
Dynodwyr allanol	OMIM: 605528 HomoloGene: 3927 GeneCards: NEU2
Patrwm RNA pattern Rhagor o gyfeiriadau
Ontoleg y genyn Gweithrediad moleciwlaidd • exo-alpha-(2->6)-sialidase activity • exo-alpha-(2->8)-sialidase activity • hydrolase activity, acting on glycosyl bonds • GO:0001948, GO:0016582 protein binding • exo-alpha-(2->3)-sialidase activity • hydrolase activity • exo-alpha-sialidase activity Cydrannau o'r gell • cytoplasm • bilen • intracellular membrane-bounded organelle • cytosol • catalytic complex Prosesau biolegol • glycosphingolipid metabolic process • lipid metabolism • lipid catabolic process • oligosaccharide catabolic process • metabolaeth • ganglioside catabolic process • cellular oligosaccharide catabolic process • carbohydrate metabolic process Sources:Amigo / QuickGO
Orthologau
Species	Bod dynol	Llygoden
Entrez	4759	n/a
Ensembl	ENSG00000115488	n/a
UniProt	Q9Y3R4	n/a
RefSeq (mRNA)	NM_005383	n/a
RefSeq (protein)	NP_005374	n/a
Lleoliad (UCSC)	n/a	n/a
PubMed search	[1]	n/a
Wicidata
Gweld/Golygu Bod dynol

Protein sy'n cael ei godio yn y corff dynol gan y genyn NEU2 yw NEU2 a elwir hefyd yn Neuraminidase 2 (Saesneg). Segment o DNA yw'r genyn, sy'n amgodio ffwythiant arbennig. Mae'r genyn yma wedi ei leoli ar yr edefyn blaen o gromosom dynol 2, band 2q37.1.^[2]

Yn aml mae gan enynnau lawer o gyfystyron. Mae hyn oherwydd eu bod yn aml yn cael eu darganfod gan nifer o bobl mewn cyd-destunau gwahanol heb wybod mai'r un genynnau oeddyn nhw. Hefyd mae gan wahanol gymunedau gwyddonol safonau gwahanol ar gyfer enwi genynnau. Dyma restr o gyfystyron ar gyfer y genyn NEU2.

• SIAL2

• "Membrane restructuring following in situ sialidase digestion of gangliosides: Complex model bilayers by synchrotron radiation reflectivity. ". Biochim Biophys Acta. 2017. PMID 28087363.
• "Looking at human cytosolic sialidase NEU2 structural features with an interdisciplinary approach. ". Biochemistry. 2014. PMID 25033330.
• "Preliminary crystallographic analysis of neuraminidase N2 from a new influenza A virus. ". Acta Crystallogr Sect F Struct Biol Cryst Commun. 2013. PMID 23908028.
• "Human cytosolic sialidase NEU2-low general tissue expression but involvement in PC-3 prostate cancer cell survival. ". Biochem Biophys Res Commun. 2012. PMID 23068092.
• "Defective myogenic differentiation of human rhabdomyosarcoma cells is characterized by sialidase Neu2 loss of expression.". Cell Biol Int. 2009. PMID 19524683.