Glicerol-3-fosfat O-aciltransferaza
Glicerol-3-fosfat O-aciltransferaza (EC 2.3.1.15, alfa-glicerofosfatna aciltransferaza, 3-glicerofosfatna aciltransferaza, ACP:sn-glicerol-3-fosfatna aciltransferaza, glicerol 3-fosfatna aciltransferaza, glicerol fosfatna aciltransferaza, glicerol fosfatna transacilaza, glicerofosfatna aciltransferaza, glicerofosfatna transacilaza, sn-glicerol 3-fosfatna aciltransferaza, sn-glicerol-3-fosfatna aciltransferaza, glicerol-3-fosfatna O-aciltransferaza) je enzim sa sistematskim imenom acil-KoA:sn-glicerol-3-fosfat 1-O-aciltransferaza.[1][2][3][4] Ovaj enzim katalizuje sledeću hemijsku reakciju
| Glicerol-3-fosfat O-aciltransferaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 2.3.1.15 | ||||||||
| CAS broj | 9029-96-3 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
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- acil-KoA + sn-glicerol 3-fosfat KoA + 1-acil-sn-glicerol 3-fosfat
Acil-[acil-nosilac protein] takođe može da deluje kao acil donor.
Reference
uredi- ↑ Bertrams, M. and Heinz, E. (1981). „Positional specificity and fatty-acid selectivity of purified sn-glycerol 3-phosphate acyltransferases from chloroplasts”. Plant Physiol. 68: 653-657. PMID 16661974.
- ↑ Frentzen, M., Heinz, E., McKeon, T.A. and Stumpf, P.K. (1983). „Specificities and selectivities of glycerol-3-phosphate acyltransferase and monoacylglycerol-3-phosphate acyltransferase from pea and spinach chloroplasts”. Eur. J. Biochem. 129: 629-636. PMID 6825679.
- ↑ Green, P.R., Merrill, A.H. and Bell, R.M. (1981). „Membrane phospholipid synthesis in Escherichia coli. Purification, reconstitution, and characterization of sn-glycerol-3-phosphate acyltransferase”. J. Biol. Chem. 256: 11151-11159. PMID 6350296.
- ↑ Yamashita, S. and Numa, N. (1972). „Partial purification and properties of glycerophosphate acyltransferase from rat liver. Formation of 1-acylglycerol 3-phosphate from sn-glycerol 3-phosphate and palmityl coenzyme A”. Eur. J. Biochem. 31: 565-573. PMID 4650158.
Literatura
uredi- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.