(Q277785)

PERINDOPRIL (English)

(2S,3aR,7aS)-1-[(2S)-2-[[(2S)-1-ethoxy-1-oxopentan-2-yl]amino]-1-oxopropyl]-2,3,3a,4,5,6,7,7a-octahydroindole-2-carboxylic acid

18 November 2016

stereoisomer of

1 reference

based on heuristic

inferred from InChI

chemical formula

C₁₉H₃₂N₂O₅

1 reference

PERINDOPRIL (English)

18 November 2016

canonical SMILES

CCCC(C(=O)OCC)NC(C)C(=O)N1C2CCCCC2CC1C(=O)O

1 reference

PERINDOPRIL (English)

18 November 2016

isomeric SMILES

CCC[C@@H](C(=O)OCC)N[C@@H](C)C(=O)N1[C@H]2CCCC[C@H]2C[C@H]1C(=O)O

1 reference

PERINDOPRIL (English)

https://www.whocc.no/atc_ddd_index/?code=C09AA04

18 November 2016

defined daily dose

4 milligram

route of administration

oral administration

1 reference

reference URL

1 reference

14 February 2018

World Health Organisation international non-proprietary name

perindopril (English)

1 reference

perindopril (English)

medical condition treated

3 October 2016

congestive heart failure

1 reference

13 December 2016

arterial hypertension

2 references

13 December 2016

Drug Indications Extracted from FAERS

Food and Drug Administration

2 October 2018

coronary artery disease

start time

30 December 1993

approved by

1 reference

Inxight: Drugs Database

https://drugs.ncats.io/drug/Y5GMK36KGY

2 November 2018

reference URL

http://www.accessdata.fda.gov/drugsatfda_docs/label/2015/020184s022lbl.pdf

arterial hypertension

start time

30 December 1993

approved by

Food and Drug Administration

1 reference

Inxight: Drugs Database

https://drugs.ncats.io/drug/Y5GMK36KGY

2 November 2018

reference URL

https://www.drugs.com/pro/perindopril.html

significant drug interaction

1 reference

A reference set of clinically relevant adverse drug-drug interactions

1 reference

A reference set of clinically relevant adverse drug-drug interactions

1 reference

A reference set of clinically relevant adverse drug-drug interactions

1 reference

A reference set of clinically relevant adverse drug-drug interactions

1 reference

A reference set of clinically relevant adverse drug-drug interactions

1 reference

A reference set of clinically relevant adverse drug-drug interactions

1 reference

A reference set of clinically relevant adverse drug-drug interactions

1 reference

A reference set of clinically relevant adverse drug-drug interactions

1 reference

A reference set of clinically relevant adverse drug-drug interactions

1 reference

A reference set of clinically relevant adverse drug-drug interactions

1 reference

A reference set of clinically relevant adverse drug-drug interactions

1 reference

A reference set of clinically relevant adverse drug-drug interactions

1 reference

A reference set of clinically relevant adverse drug-drug interactions

1 reference

A reference set of clinically relevant adverse drug-drug interactions

1 reference

A reference set of clinically relevant adverse drug-drug interactions

1 reference

A reference set of clinically relevant adverse drug-drug interactions

heparin

1 reference

A reference set of clinically relevant adverse drug-drug interactions

triamterene

1 reference

A reference set of clinically relevant adverse drug-drug interactions

amiloride

1 reference

A reference set of clinically relevant adverse drug-drug interactions

trimethoprim

1 reference

A reference set of clinically relevant adverse drug-drug interactions

cyclosporine

1 reference

A reference set of clinically relevant adverse drug-drug interactions

eplerenone

1 reference

A reference set of clinically relevant adverse drug-drug interactions

spironolactone

1 reference

A reference set of clinically relevant adverse drug-drug interactions

nabumetone

1 reference

A reference set of clinically relevant adverse drug-drug interactions

naproxen

1 reference

A reference set of clinically relevant adverse drug-drug interactions

celecoxib

1 reference

A reference set of clinically relevant adverse drug-drug interactions

Diclofenac

1 reference

A reference set of clinically relevant adverse drug-drug interactions

piroxicam

1 reference

A reference set of clinically relevant adverse drug-drug interactions

meloxicam

1 reference

A reference set of clinically relevant adverse drug-drug interactions

(RS)-fenoprofen

1 reference

A reference set of clinically relevant adverse drug-drug interactions

(+-)-flurbiprofen

1 reference

A reference set of clinically relevant adverse drug-drug interactions

ibuprofen

1 reference

A reference set of clinically relevant adverse drug-drug interactions

indomethacin

1 reference

A reference set of clinically relevant adverse drug-drug interactions

(RS)-ketoprofen

1 reference

A reference set of clinically relevant adverse drug-drug interactions

(RS)-etodolac

1 reference

A reference set of clinically relevant adverse drug-drug interactions

sulindac

1 reference

A reference set of clinically relevant adverse drug-drug interactions

parecoxib

1 reference

A reference set of clinically relevant adverse drug-drug interactions

tenoxicam

1 reference

A reference set of clinically relevant adverse drug-drug interactions

eplerenone

1 reference

A reference set of clinically relevant adverse drug-drug interactions

bendroflumethiazide

1 reference

A reference set of clinically relevant adverse drug-drug interactions

chlorthalidone

1 reference

A reference set of clinically relevant adverse drug-drug interactions

(2RS,6RS)-clopamide

1 reference

A reference set of clinically relevant adverse drug-drug interactions

bromocriptine

1 reference

A reference set of clinically relevant adverse drug-drug interactions

bumetanide

1 reference

A reference set of clinically relevant adverse drug-drug interactions

furosemide

1 reference

A reference set of clinically relevant adverse drug-drug interactions

spironolactone

1 reference

A reference set of clinically relevant adverse drug-drug interactions

hydrochlorothiazide

1 reference

A reference set of clinically relevant adverse drug-drug interactions

indapamide

1 reference

A reference set of clinically relevant adverse drug-drug interactions

nabumetone

1 reference

A reference set of clinically relevant adverse drug-drug interactions

nabumetone

1 reference

A reference set of clinically relevant adverse drug-drug interactions

naproxen

1 reference

A reference set of clinically relevant adverse drug-drug interactions

naproxen

1 reference

A reference set of clinically relevant adverse drug-drug interactions

celecoxib

1 reference

A reference set of clinically relevant adverse drug-drug interactions

celecoxib

1 reference

A reference set of clinically relevant adverse drug-drug interactions

Diclofenac

1 reference

A reference set of clinically relevant adverse drug-drug interactions

Diclofenac

1 reference

A reference set of clinically relevant adverse drug-drug interactions

piroxicam

1 reference

A reference set of clinically relevant adverse drug-drug interactions

piroxicam

1 reference

A reference set of clinically relevant adverse drug-drug interactions

meloxicam

1 reference

A reference set of clinically relevant adverse drug-drug interactions

meloxicam

1 reference

A reference set of clinically relevant adverse drug-drug interactions

(RS)-fenoprofen

1 reference

A reference set of clinically relevant adverse drug-drug interactions

(RS)-fenoprofen

1 reference

A reference set of clinically relevant adverse drug-drug interactions

(+-)-flurbiprofen

1 reference

A reference set of clinically relevant adverse drug-drug interactions

(+-)-flurbiprofen

1 reference

A reference set of clinically relevant adverse drug-drug interactions

ibuprofen

1 reference

A reference set of clinically relevant adverse drug-drug interactions

ibuprofen

1 reference

A reference set of clinically relevant adverse drug-drug interactions

indomethacin

1 reference

A reference set of clinically relevant adverse drug-drug interactions

indomethacin

1 reference

A reference set of clinically relevant adverse drug-drug interactions

(RS)-ketoprofen

1 reference

A reference set of clinically relevant adverse drug-drug interactions

(RS)-ketoprofen

1 reference

A reference set of clinically relevant adverse drug-drug interactions

(RS)-etodolac

1 reference

A reference set of clinically relevant adverse drug-drug interactions

(RS)-etodolac

1 reference

A reference set of clinically relevant adverse drug-drug interactions

sulindac

1 reference

A reference set of clinically relevant adverse drug-drug interactions

sulindac

1 reference

A reference set of clinically relevant adverse drug-drug interactions

parecoxib

1 reference

A reference set of clinically relevant adverse drug-drug interactions

parecoxib

1 reference

A reference set of clinically relevant adverse drug-drug interactions

tenoxicam

1 reference

A reference set of clinically relevant adverse drug-drug interactions

tenoxicam

1 reference

A reference set of clinically relevant adverse drug-drug interactions

1 reference

A reference set of clinically relevant adverse drug-drug interactions

1 reference

A reference set of clinically relevant adverse drug-drug interactions

1 reference

A reference set of clinically relevant adverse drug-drug interactions

1 reference

A reference set of clinically relevant adverse drug-drug interactions

1 reference

A reference set of clinically relevant adverse drug-drug interactions

1 reference

A reference set of clinically relevant adverse drug-drug interactions

1 reference

A reference set of clinically relevant adverse drug-drug interactions

1 reference

A reference set of clinically relevant adverse drug-drug interactions

1 reference

A reference set of clinically relevant adverse drug-drug interactions

1 reference

A reference set of clinically relevant adverse drug-drug interactions

1 reference

A reference set of clinically relevant adverse drug-drug interactions

1 reference

A reference set of clinically relevant adverse drug-drug interactions

1 reference

A reference set of clinically relevant adverse drug-drug interactions

1 reference

A reference set of clinically relevant adverse drug-drug interactions

1 reference

A reference set of clinically relevant adverse drug-drug interactions

1 reference

A reference set of clinically relevant adverse drug-drug interactions

1 reference

A reference set of clinically relevant adverse drug-drug interactions

1 reference

A reference set of clinically relevant adverse drug-drug interactions

1 reference

A reference set of clinically relevant adverse drug-drug interactions

1 reference

A reference set of clinically relevant adverse drug-drug interactions

1 reference

A reference set of clinically relevant adverse drug-drug interactions

1 reference

A reference set of clinically relevant adverse drug-drug interactions

1 reference

A reference set of clinically relevant adverse drug-drug interactions

1 reference

A reference set of clinically relevant adverse drug-drug interactions

bendroflumethiazide

1 reference

A reference set of clinically relevant adverse drug-drug interactions

chlorthalidone

1 reference

A reference set of clinically relevant adverse drug-drug interactions

(2RS,6RS)-clopamide

1 reference

A reference set of clinically relevant adverse drug-drug interactions

hydrochlorothiazide

1 reference

A reference set of clinically relevant adverse drug-drug interactions

indapamide

1 reference

A reference set of clinically relevant adverse drug-drug interactions

cyclosporine

1 reference

A reference set of clinically relevant adverse drug-drug interactions

bromocriptine

hyperinsulinism

1 reference

A reference set of clinically relevant adverse drug-drug interactions

bumetanide

orthostatic hypotension

1 reference

A reference set of clinically relevant adverse drug-drug interactions

furosemide

orthostatic hypotension

1 reference

A reference set of clinically relevant adverse drug-drug interactions

pregnancy category

US pregnancy category D

1 reference

imported from Wikimedia project

English Wikipedia

LiverTox likelihood score

LiverTox toxicity likelihood category E*

1 reference

8 April 2021

https://www.ncbi.nlm.nih.gov/books/n/livertox/Perindopril

last update

11 February 2018

official website

http://www.coversyl.com/

1 reference

imported from Wikimedia project

2 references

5 March 2018

Medical Subject Headings

MeSH descriptor ID

D020913

15 March 2018

antihypertensive drug

1 reference

InChI=1S/C19H32N2O5/c1-4-8-14(19(25)26-5-2)20-12(3)17(22)21-15-10-7-6-9-13(15)11-16(21)18(23)24/h12-16,20H,4-11H2,1-3H3,(H,23,24)/t12-,13-,14-,15-,16-/m0/s1

Medical Subject Headings

15 March 2018

0 references

0 references

Perindopril

0 references

Identifiers

InChI

1 reference

PERINDOPRIL (English)

18 November 2016

2 references

PERINDOPRIL (English)

18 November 2016

ChEBI release 2020-09-01

CAS Registry Number

82834-16-0

2 references

perindopril (English)

18 November 2016

https://commonchemistry.cas.org/detail?cas_rn=82834-16-0

9 April 2021

1 reference

Perindopril (English)

18 November 2016

2 references

PERINDOPRIL (English)

18 November 2016

40466996

1 reference

Reaxys registry number

4300272

1 reference

perindopril (English)

3 October 2016

ChEBI ID

8024

mapping relation type

2 references

PERINDOPRIL (English)

18 November 2016

International Chemical Identifier

InChI

InChI=1S/C19H32N2O5/c1-4-8-14(19(25)26-5-2)20-12(3)17(22)21-15-10-7-6-9-13(15)11-16(21)18(23)24/h12-16,20H,4-11H2,1-3H3,(H,23,24)/t12-,13-,14-,15-,16-/m0/s1

1 reference

PERINDOPRIL (English)

18 November 2016

2 references

inferred from InChIKey

MSBNK-Univ_Connecticut-CO000336

MassBank accession ID

0 references

MSBNK-Univ_Connecticut-CO000337

0 references

MSBNK-Univ_Connecticut-CO000338

0 references

MSBNK-Univ_Connecticut-CO000339

0 references

MSBNK-Univ_Connecticut-CO000340

0 references

MSBNK-Waters-WA002376

0 references

MSBNK-Waters-WA002377

0 references

MSBNK-Waters-WA002378

0 references

MSBNK-Waters-WA002379

0 references

MSBNK-Waters-WA002380

0 references

MSBNK-Waters-WA002381

0 references

SPLASH

splash10-00dj-9700000000-6c619894c334e6d16e0d

0 references

DSSTox substance ID

DTXSID6023440

2 references

Mapping file of InChIStrings, InChIKeys and DTXSIDs for the EPA CompTox Dashboard

DSSTOX compound identifier

0 references

0 references

0 references

ECHA Substance Infocard ID

100.120.843

1 reference

ECHA Substance Infocard database

ECHA Substance Infocard ID

100.120.843

27 December 2018

1H-Indole-2-carboxylic acid, 1-[(2S)-2-[[(1S)-1-(ethoxycarbonyl)butyl]amino]-1-oxopropyl]octahydro-, (2S,3aS,7aS)- (English)

quotation

CAS no.: 82834-16-0 (English)

1 reference

Guide to Pharmacology Ligand ID

Perindopril (English)

publication date

17 November 2015

6367

1 reference

IUPHAR/BPS Guide to PHARMACOLOGY

Guide to Pharmacology Ligand ID

6367

perindopril (English)

18 November 2016

Perindopril

0 references

0 references

0 references

1 reference

perindopril (English)

18 November 2016

DrugBank ID

DB00790

1 reference

Human Metabolome Database ID

HMDB0014928

2 references

based on heuristic

inferred from InChIKey

2 references

perindopril (English)

18 November 2016

MedlinePlus drug identifier

0 references

1 reference

perindopril (English)

18 November 2016

0 references

1 reference

1 reference

perindopril (English)

3 October 2016

1 reference

https://docs.openalex.org/download-snapshot/snapshot-data-format

perindopril (English)

3 October 2016

0 references

1 reference

28 October 2013

Microsoft Academic ID

0 references

1 reference

26 January 2022

UMLS CUI

C0136123

1 reference

perindopril (English)