English: Streptococcus pyogenes Cas9 bound to sgRNA (purple) and target DNA (blue) duplex. The recognition lobe (orange) is essential for binding sgRNA and DNA and the nuclease lobe (red) hydrolyses the target DNA. PDB: 4OO8
Date
(upload to Wikimedia Commons), 31 January 2014 (deposition at PDB)
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Captions
Streptococcus pyogenes Cas9 bound to sgRNA and target DNA duplex. PDB: 4OO8