File:Streptococcus pyogenes Cas9-DNA-RNA complex PDB 4OO8.png

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Summary

Description
English: Streptococcus pyogenes Cas9 bound to sgRNA (purple) and target DNA (blue) duplex. The recognition lobe (orange) is essential for binding sgRNA and DNA and the nuclease lobe (red) hydrolyses the target DNA. PDB: 4OO8
Date (upload to Wikimedia Commons),
31 January 2014 (deposition at PDB)
Source Atom coordinates: https://www.rcsb.org/structure/4OO8; Visualization: Own work
Author Deposition authors: Nishimasu, H., Ishitani, R., Nureki, O.;
Visualization author: Synpath

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Captions

Streptococcus pyogenes Cas9 bound to sgRNA and target DNA duplex. PDB: 4OO8

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21 June 2023

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