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Are basal D-serine plasma levels a predictive biomarker for the rapid antidepressant effects of ketamineand ketamine metabolites?

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Acknowledgments

The work cited in this response was supported by funds from the Intramural Research Program of the National Institute on Aging of the US National Institutes of Health.

Conflict of interest

Irving W. Wainer is listed as the lead inventor on a patent application for the use of (2S,6S)-hydroxynorketamine and other ketamine metabolites in the treatment of depression and neuropathic pain. Dr. Wainer has assigned his rights in the patent to the U.S. Government but will receive a percentage of any royalties that may be received by the government.

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Correspondence to Irving W. Wainer.

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Wainer, I.W. Are basal D-serine plasma levels a predictive biomarker for the rapid antidepressant effects of ketamineand ketamine metabolites?. Psychopharmacology 231, 4083–4084 (2014). https://doi.org/10.1007/s00213-014-3736-6

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  • DOI: https://doi.org/10.1007/s00213-014-3736-6

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