File:Fimmu-14-1219895-g001.jpg

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Osteomyelitis

Summary

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Description
English: Figure 1 S. aureus exerts a negative effect on the host immune system. Macrophage migration is mediated by MMP9 and MMP3, and neutrophils are inhibited by virulence factors CHIP and FPRL1. S. aureus escapes the immune effects of neutrophils by biofilm formation, NET formation, and intracellular survival. Different oxygen and nutrient conditions can cause macrophages to differentiate into different cell subtypes and thus have different effects on inflammation. Checkpoints such as CTLA-4, PD-1, LAG-3, and TIM-3 inhibit T cell immune effect. Antibodies ASN-1 and ASN-2 can neutralize virulence factors such as Hla, PVL, and LukED.
Date
Source https://www.frontiersin.org/articles/10.3389/fimmu.2023.1219895/full
Author Yingqi Chen,Zixian Liu, Zexin Lin, Mincheng Lu, Yong Fu, Guanqiao Liu, Bin Yu

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current00:02, 8 December 2023Thumbnail for version as of 00:02, 8 December 20232,008 × 1,175 (260 KB)Ozzie10aaaa (talk | contribs)Uploaded a work by Yingqi Chen,Zixian Liu, Zexin Lin, Mincheng Lu, Yong Fu, Guanqiao Liu, Bin Yu from https://www.frontiersin.org/articles/10.3389/fimmu.2023.1219895/full with UploadWizard

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