File:Filament-Depolymerization-Can-Explain-Chromosome-Pulling-during-Bacterial-Mitosis-pcbi.1002145.s011.ogv

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English: Stretching of the ParB polymer. When the maximum ParA disassembly rate, , is sufficiently large, the ParB polymer does not have time to relax to its equilibrium shape as it is pulled, and therefore stretches out. The ParB polymer consists of three segments; the two peripheral segments (light green), which cannot bind to ParA, and the central segment (dark green), which can bind to ParA. Note that the peripheral segments of the ParB polymer stretch, while the central segment of the ParB polymer is initially bound to the ParA filament bundle. When the peripheral segments stretch too far, they start to stretch the central segment, thus decreasing the length, , that the ParB polymer penetrates into the ParA bundle. This can lead to detachment for sufficiently high . In this movie, , five times greater than the ParA disassembly rate, , in our standard simulations (see Fig. 3 caption).
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Source Video S3 from Banigan E, Gelbart M, Gitai Z, Wingreen N, Liu A (2011). "Filament Depolymerization Can Explain Chromosome Pulling during Bacterial Mitosis". PLOS Computational Biology. DOI:10.1371/journal.pcbi.1002145. PMID 21966261. PMC: 3178632.
Author Banigan E, Gelbart M, Gitai Z, Wingreen N, Liu A
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current20:28, 14 November 201232 s, 1,036 × 690 (11.71 MB)Open Access Media Importer Bot (talk | contribs)Automatically uploaded media file from Open Access source. Please report problems or suggestions here.

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