AmiGO 2: Term Details for "intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress" (GO:0070059)

Term Information

Accession: GO:0070059
Name: intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress
Ontology: biological_process
Synonyms: ER stress-induced apoptosis, apoptosis in response to ER stress, apoptosis triggered by ER stress, endoplasmic reticulum stress-induced apoptosis, intrinsic apoptotic signaling pathway induced by endoplasmic reticulum stress, apoptosis in response to endoplasmic reticulum stress
Alternate IDs: None
Definition: The series of molecular signals in which an intracellular signal is conveyed to trigger the apoptotic death of a cell. The pathway is induced in response to a stimulus indicating endoplasmic reticulum (ER) stress, and ends when the execution phase of apoptosis is triggered. ER stress usually results from the accumulation of unfolded or misfolded proteins in the ER lumen. Source: PMID:18701708, GOC:mah, GOC:mtg_apoptosis
Comment: None
History: See term history for GO:0070059 at QuickGO
Chem. react.: None
Subset: None
Related: Link to all genes and gene products annotated to intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress (excluding "regulates").; Link to all direct and indirect annotations to intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress (excluding "regulates").; Link to all direct and indirect annotations download (limited to first 10,000) for intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress (excluding "regulates").

Include "regulates"
For more information, please see the ontology relation documentation.

Filter results

View this term in QuickGO.

Additional external viewing options

OLSVis (interactive)

Additional internal viewing options

CARO:0030000 biological entity
CARO:0000000 anatomical entity
UBERON:0001062 anatomical entity
GO:0008150 biological_process
CARO:0000006 material anatomical entity
GO:0065007 biological regulation
GO:0009987 cellular process
CARO:0000003 connected anatomical structure
UBERON:0000465 material anatomical entity
UBERON:0000061 anatomical structure
GO:0008219 cell death
GO:0005575 cellular_component
GO:0050789 regulation of biological process
CL:0000000 cell
GO:0007154 cell communication
GO:0110165 cellular anatomical structure
GO:0051716 cellular response to stimulus
GO:0012501 programmed cell death
GO:0050794 regulation of cellular process
GO:0050896 response to stimulus
GO:0023052 signaling
GO:0006915 apoptotic process
GO:0005622 intracellular anatomical structure
GO:0006950 response to stress
GO:0007165 signal transduction
GO:0097190 apoptotic signaling pathway
GO:0033554 cellular response to stress
GO:0035556 intracellular signal transduction
GO:0097193 intrinsic apoptotic signaling pathway
GO:0034976 response to endoplasmic reticulum stress
GO:0070059 intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress
GO:1902236 negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway
GO:0036483 neuron intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress
GO:1902237 positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway
GO:1902235 regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway

Parents of intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress (GO:0070059)

subject	relation	object
intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress	is_a	response to endoplasmic reticulum stress (GO:0034976)
intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress	is_a	intrinsic apoptotic signaling pathway (GO:0097193)
intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress	RO:0002162	Opisthokonta (NCBITaxon:33154)

Children of intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress (GO:0070059)

subject	relation	object
regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway (GO:1902235)	RO:0002211	intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress
neuron intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress (GO:0036483)	is_a	intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress
negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway (GO:1902236)	RO:0002212	intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress
positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway (GO:1902237)	RO:0002213	intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress

GONUTS Add usage comments for this term on the GONUTS wiki.